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Semaglutide is actually FDA-approved for type 2 diabetes (as Ozempic) at lower doses, reflecting its robust effects on blood sugar regulation

The range reflects a difference in assumptions: Do GLP-1s prevent diabetes for four years (similar to clinical trial results) or will these benefits extend over a lifetime

Free Radic Biol Med 25: 242-249, 1998

In this respect, GLP-1s have an added benefit for MASH patients since they have been shown to reduce the rate of major cardiovascular events, including strokes and heart attacks

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